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ZINC ID                   RADAR Physiochemical Propperties Lipophilicity Water solubility Phyarmacokinetics Druglikeness Medicinal Chemistry
20878000

Nc1nnnn1NCc1ccc2c(c1)OCCO2		 Formula:C10H12N6O2
Mol: 248.24
Heavy atoms:18
Aromatic heavy atoms: 11
Fraction Csp3: 0.30
Rotatable bonds: 3
H-bond acceptors: 5
H-bond donors: 2
MR: 62.62
TPSA: 100.11
ILOGP:1.74
XLOGP3: 0.84
WLOGP: -0.56
MLOGP: 1.12
Silicos ITLogP: -0.59
Consensus LogP: 0.51
 ESOL
LogS:-2.16
Solubility(mg/ml): 1.710000
Solubility(mol/l):0.006880
Class:Soluble

Ali
LogS:-2.53
Solubility(mg/ml): 0.741000
Solubility(mol/l): 0.002980
Class:Soluble

SilicosIT
LogS:-2.32
Solubility(mg/ml): 1.190000
Solubility(mol/l): 0.004810
Class:Soluble
GIAbsorption:High
BBB permeant: No
Pgp substrate: Yes
CYP1A2 inhibitor: Yes
CYP2C19:  No
CYP2C9:  No
CYP2D6:  No
CYP3A4:  No
Log kp:  -7.22
Lipinski:0
Ghose: 1
Veber: 0
Egan: 0
Muegge: 0
Bioavalability Score0.55
PAINS:0
Brenk: 0
Leadlikeness: 1
Synthetic Accessibility: 2.65