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ZINC ID                   RADAR Physiochemical Propperties Lipophilicity Water solubility Phyarmacokinetics Druglikeness Medicinal Chemistry
17354631

Nc1ncc2c(n1)nc([nH]2)[C@@H](c1ccccc1)O		 Formula:C12H11N5O
Mol: 241.25
Heavy atoms:18
Aromatic heavy atoms: 15
Fraction Csp3: 0.08
Rotatable bonds: 2
H-bond acceptors: 4
H-bond donors: 3
MR: 66.70
TPSA: 100.71
ILOGP:1.27
XLOGP3: 0.60
WLOGP: 0.70
MLOGP: -0.02
Silicos ITLogP: 1.28
Consensus LogP: 0.77
 ESOL
LogS:-2.20
Solubility(mg/ml): 1.530000
Solubility(mol/l):0.006330
Class:Soluble

Ali
LogS:-2.29
Solubility(mg/ml): 1.240000
Solubility(mol/l): 0.005140
Class:Soluble

SilicosIT
LogS:-3.80
Solubility(mg/ml): 0.037900
Solubility(mol/l): 0.000157
Class:Soluble
GIAbsorption:High
BBB permeant: No
Pgp substrate: No
CYP1A2 inhibitor: No
CYP2C19:  No
CYP2C9:  No
CYP2D6:  Yes
CYP3A4:  No
Log kp:  -7.35
Lipinski:0
Ghose: 0
Veber: 0
Egan: 0
Muegge: 0
Bioavalability Score0.55
PAINS:0
Brenk: 0
Leadlikeness: 1
Synthetic Accessibility: 2.69