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ZINC ID                   RADAR Physiochemical Propperties Lipophilicity Water solubility Phyarmacokinetics Druglikeness Medicinal Chemistry
12946727

Cn1ccc(n1)NC(=O)c1cc2c([nH]1)cccc2		 Formula:C13H12N4O
Mol: 240.26
Heavy atoms:18
Aromatic heavy atoms: 14
Fraction Csp3: 0.08
Rotatable bonds: 3
H-bond acceptors: 2
H-bond donors: 2
MR: 69.56
TPSA: 62.71
ILOGP:0.94
XLOGP3: 1.86
WLOGP: 1.96
MLOGP: 1.43
Silicos ITLogP: 1.60
Consensus LogP: 1.56
 ESOL
LogS:-2.88
Solubility(mg/ml): 0.317000
Solubility(mol/l):0.001320
Class:Soluble

Ali
LogS:-2.80
Solubility(mg/ml): 0.382000
Solubility(mol/l): 0.001590
Class:Soluble

SilicosIT
LogS:-4.21
Solubility(mg/ml): 0.014900
Solubility(mol/l): 0.000062
Class:Moderately soluble
GIAbsorption:High
BBB permeant: Yes
Pgp substrate: No
CYP1A2 inhibitor: Yes
CYP2C19:  No
CYP2C9:  No
CYP2D6:  No
CYP3A4:  No
Log kp:  -6.44
Lipinski:0
Ghose: 0
Veber: 0
Egan: 0
Muegge: 0
Bioavalability Score0.55
PAINS:0
Brenk: 0
Leadlikeness: 1
Synthetic Accessibility: 2.01