| HSPMdb Accession No | HSPMDB010222 |
| PMID | 30452489 |
| Target | Hsp70 |
| HSP Name | Hsp70-HDJ2 |
| Organism | Human |
| Localization | Cytosol |
| Cellular activity | Antiproliferative activity |
| Compound Name | 116-9e in combination with Hydroxyurea |
| IUPAC Name | 6-{5-[(benzyloxy)carbonyl]-4-{[1,1'-biphenyl]-4-yl}-6-methyl-2-oxo-1,2,3,4-tetrahydropyrimidin-1-yl}hexanoic acid |
| SMILES | CC1=C(C(NC(=O)N1CCCCCC(O)=O)C1=CC=C(C=C1)C1=CC=CC=C1)C(=O)OCC1=CC=CC=C1 |
| Class | Dihydropyrimidine derivative |
| Percentage Cell Growth Inhibition | 60% at 40uM 116-9e and 100 uM Hydroxyurea |
| Cellular assay | Luminescence based viability assay |
| Cellular Model | HAP1 cells |
| Disease | Cancer |
Loading Please Wait ...