HSPMdb Accession NoHSPMDB002666
PMID30126533
TargetHsp100
HSP NameClpP
OrganismHuman
LocalizationMitochondria
Enzymatic activityInhibition of protease activity
Compound NameADEP-01
SMILESO=C(N1CCC[C@]12[H])[C@@H](NC([C@@H](N(C([C@]3(N(CCC3)C([C@H](COC2=O)NC([C@H](NC(/C=C/CCCC)=O)CC4=CC=CC=C4)=O)=O)[H])=O)C)C)=O)C
ClassAcyldepsipeptide analogue
RD_Index0.22 at 1 uM
Site of InteractionNucleotide binding domain
Type of Enzymatic AssaySubstrate degradation assay (FITC-casein)

Structure



HSPMDB002666

ADEP-01

Physicochemical Properties