HSPMdb Accession NoHSPMDB002665
PMID30126533
TargetHsp100
HSP NameClpP
OrganismHuman
LocalizationMitochondria
Enzymatic activityInhibition of protease activity
Compound NameADEP-04
SMILESO=C(N1C[C@@H](C[C@]12[H])C)[C@@H](NC([C@@H](N(C([C@]3(N(CCC3)C([C@H](COC2=O)NC([C@H](NC(/C=C/C=C/CCC)=O)CC4=CC=CC=C4)=O)=O)[H])=O)C)C)=O)C
ClassAcyldepsipeptide analogue
RD_Index0.32 at 1 uM
Site of InteractionNucleotide binding domain
Type of Enzymatic AssaySubstrate degradation assay (FITC-casein)

Structure



HSPMDB002665

ADEP-04

Physicochemical Properties