HSPMdb Accession NoHSPMDB002661
PMID30126533
TargetHsp100
HSP NameClpP
OrganismHuman
LocalizationMitochondria
Enzymatic activityInhibition of protease activity
Compound NameADEP-15
SMILESO=C(N1C[C@@H](C[C@]12[H])C)[C@@H](NC([C@]3([H])CCCN3C([C@]4(N(CCC4)C([C@H](COC2=O)NC([C@H](NC(/C=C/CCCC)=O)CC5=CC(F)=CC(F)=C5)=O)=O)[H])=O)=O)C
ClassAcyldepsipeptide analogue
RD_Index0.58 at 1 uM
Site of InteractionNucleotide binding domain
Type of Enzymatic AssaySubstrate degradation assay (FITC-casein)

Structure



HSPMDB002661

ADEP-15

Physicochemical Properties