HSPMdb Accession NoHSPMDB002652
PMID30126533
TargetHsp100
HSP NameClpP
OrganismHuman
LocalizationMitochondria
Enzymatic activityInhibition of protease activity
Compound NameADEP-41
SMILESO=C(N1CCC[C@]12[H])[C@@H](NC([C@]3(N(C([C@]4(N(CCC4)C([C@H]([C@@H](OC2=O)C)NC([C@@H](NC(/C=C/CCCC)=O)CC5=CC(F)=CC(F)=C5)=O)=O)[H])=O)CCCC3)[H])=O)C
ClassAcyldepsipeptide analogue
RD_Index0.79 at 1 uM
Site of InteractionNucleotide binding domain
Type of Enzymatic AssaySubstrate degradation assay (FITC-casein)

Structure



HSPMDB002652

ADEP-41

Physicochemical Properties