HSPMdb Accession NoHSPMDB002642
PMID30126533
TargetHsp100
HSP NameClpP
OrganismHuman
LocalizationMitochondria
Enzymatic activityInhibition of protease activity
Compound NameADEP-18
SMILESO=C([C@H](C)NC([C@H](C)N(C)C([C@@]1([H])N(C([C@@H](NC([C@H](CC2=CC=CC=C2)NC(/C=C/CCCCC)=O)=O)CO3)=O)CCC1)=O)=O)N4CCC[C@@]4([H])C3=O
ClassAcyldepsipeptide analogue
RD_Index0.72 at 5 uM
Site of InteractionNucleotide binding domain
Type of Enzymatic AssaySubstrate degradation assay (FITC-casein)

Structure



HSPMDB002642

ADEP-18

Physicochemical Properties