HSPMdb Accession NoHSPMDB002629
PMID30126533
TargetHsp100
HSP NameClpP
OrganismHuman
LocalizationMitochondria
Enzymatic activityInhibition of protease activity
Compound NameADEP-28
SMILESO=C([C@H](C)NC([C@@]1([H])N(CC[C@H](C)C1)C([C@@]2([H])N(C([C@@H](NC([C@H](CC3=CC(F)=CC(F)=C3)NC(/C=C/CCCC)=O)=O)[C@H](C)O4)=O)CCC2)=O)=O)N5CCC[C@@]5([H])C4=O
ClassAcyldepsipeptide analogue
RD_Index0.93 at 5 uM
Site of InteractionNucleotide binding domain
Type of Enzymatic AssaySubstrate degradation assay (FITC-casein)

Structure



HSPMDB002629

ADEP-28

Physicochemical Properties