HSPMdb Accession NoHSPMDB002623
PMID30126533
TargetHsp100
HSP NameClpP
OrganismHuman
LocalizationMitochondria
Enzymatic activityInhibition of protease activity
Compound NameADEP-22
SMILESO=C([C@H](C)NC([C@H](C)N(C)C([C@@]1([H])N(C([C@@H](NC([C@H](CC2=CC=CC=C2)NC(OCC3=CC=CC=C3)=O)=O)CO4)=O)CCC1)=O)=O)N5CCC[C@@]5([H])C4=O
ClassAcyldepsipeptide analogue
RD_Index5 at 25 uM
Site of InteractionNucleotide binding domain
Type of Enzymatic AssaySubstrate degradation assay (FITC-casein)

Structure



HSPMDB002623

ADEP-22

Physicochemical Properties