HSPMdb Accession NoHSPMDB002619
PMID30126533
TargetHsp100
HSP NameClpP
OrganismHuman
LocalizationMitochondria
Enzymatic activityInhibition of protease activity
Compound NameADEP-24
SMILESO=C([C@H](C)NC([C@@]1([H])N(CCCC1)C([C@@]2([H])N(C([C@@H](NC([C@H](CC3=CC=CC=C3)NC(C4=CC=C([N+]([O-])=O)C=C4)=O)=O)CO5)=O)CCC2)=O)=O)N6CCC[C@@]6([H])C5=O
ClassAcyldepsipeptide analogue
RD_Index1 at 25 uM
Site of InteractionNucleotide binding domain
Type of Enzymatic AssaySubstrate degradation assay (FITC-casein)

Structure



HSPMDB002619

ADEP-24

Physicochemical Properties