HSPMdb Accession No | HSPMDB002619 |
PMID | 30126533 |
Target | Hsp100 |
HSP Name | ClpP |
Organism | Human |
Localization | Mitochondria |
Enzymatic activity | Inhibition of protease activity |
Compound Name | ADEP-24 |
SMILES | O=C([C@H](C)NC([C@@]1([H])N(CCCC1)C([C@@]2([H])N(C([C@@H](NC([C@H](CC3=CC=CC=C3)NC(C4=CC=C([N+]([O-])=O)C=C4)=O)=O)CO5)=O)CCC2)=O)=O)N6CCC[C@@]6([H])C5=O |
Class | Acyldepsipeptide analogue |
RD_Index | 1 at 25 uM |
Site of Interaction | Nucleotide binding domain |
Type of Enzymatic Assay | Substrate degradation assay (FITC-casein) |