HSPMdb Accession NoHSPMDB002617
PMID30126533
TargetHsp100
HSP NameClpP
OrganismHuman
LocalizationMitochondria
Enzymatic activityInhibition of protease activity
Compound NameADEP-46
SMILESO=C([C@H](C)NC([C@H](C)N(C)C([C@@]1([H])N(C([C@@H](NC([C@H](CC2=CC=CC=C2)NC(/C=C/C=C/COC3([H])OCCCC3)=O)=O)CO4)=O)CCC1)=O)=O)N5C[C@H](C)C[C@@]5([H])C4=O
ClassAcyldepsipeptide analogue
RD_Index0.02 at 25 uM
Site of InteractionNucleotide binding domain
Type of Enzymatic AssaySubstrate degradation assay (FITC-casein)

Structure



HSPMDB002617

ADEP-46

Physicochemical Properties