HSPMdb Accession NoHSPMDB002613
PMID30126533
TargetHsp100
HSP NameClpP
OrganismHuman
LocalizationMitochondria
Enzymatic activityInhibition of protease activity
Compound NameADEP-45
SMILESO=C([C@H](C)NC([C@@]1([H])N(CCCC1)C([C@@]2([H])N(C([C@@H](NC([C@H](CC(C(F)=C3F)=C(F)C(F)=C3F)NC(/C=C/CCCC)=O)=O)CO4)=O)CCC2)=O)=O)N5C[C@H](C)C[C@@]5([H])C4=O
ClassAcyldepsipeptide analogue
RD_Index0.29 at 25 uM
Site of InteractionNucleotide binding domain
Type of Enzymatic AssaySubstrate degradation assay (FITC-casein)

Structure



HSPMDB002613

ADEP-45

Physicochemical Properties