HSPMdb Accession NoHSPMDB002612
PMID30126533
TargetHsp100
HSP NameClpP
OrganismHuman
LocalizationMitochondria
Enzymatic activityInhibition of protease activity
Compound NameADEP-19
SMILESO=C([C@H](C)NC([C@H](C)N(C)C([C@@]1([H])N(C([C@@H](NC([C@H](CC2=CC=CC=C2)NC(/C=C\CCCC)=O)=O)CO3)=O)CCC1)=O)=O)N4CCC[C@@]4([H])C3=O
ClassAcyldepsipeptide analogue
RD_Index0.34 at 25 uM
Site of InteractionNucleotide binding domain
Type of Enzymatic AssaySubstrate degradation assay (FITC-casein)

Structure



HSPMDB002612

ADEP-19

Physicochemical Properties