HSPMdb Accession NoHSPMDB002610
PMID30126533
TargetHsp100
HSP NameClpP
OrganismHuman
LocalizationMitochondria
Enzymatic activityInhibition of protease activity
Compound NameADEP-44
SMILESO=C([C@H](C)NC([C@@]1([H])N(CC[C@H](C)C1)C([C@@]2([H])N(C([C@@H](NC([C@H](CC3=CC(F)=CC(F)=C3)NC(/C=C/C4=CC=CC=C4C(F)(F)F)=O)=O)[C@H](C)O5)=O)CCC2)=O)=O)N6C[C@H](C)C[C@@]6([H])C5=O
ClassAcyldepsipeptide analogue
RD_Index0.42 at 25 uM
Site of InteractionNucleotide binding domain
Type of Enzymatic AssaySubstrate degradation assay (FITC-casein)

Structure



HSPMDB002610

ADEP-44

Physicochemical Properties