HSPMdb Accession NoHSPMDB002599
PMID30126533
TargetHsp100
HSP NameClpP
OrganismHuman
LocalizationMitochondria
Enzymatic activityInhibition of protease activity
Compound NameADEP-37
SMILESO=C([C@H](C)NC([C@@]1([H])N(CCC2=C1C=CC=C2)C([C@@]3([H])N(C([C@@H](NC([C@H](CC4=CC(F)=CC(F)=C4)NC(/C=C/CCCC)=O)=O)CO5)=O)CCC3)=O)=O)N6C[C@H](C)C[C@@]6([H])C5=O
ClassAcyldepsipeptide analogue
RD_Index0.92 at 25 uM
Site of InteractionNucleotide binding domain
Type of Enzymatic AssaySubstrate degradation assay (FITC-casein)

Structure



HSPMDB002599

ADEP-37

Physicochemical Properties