HSPMdb Accession NoHSPMDB002584
PMID30126533
TargetHsp100
HSP NameClpP
OrganismHuman
LocalizationMitochondria
Enzymatic activityInhibition of protease activity
Compound NameADEP-20
SMILESO=C([C@H](C)NC([C@@]1([H])N(CCCC1)C([C@@]2([H])N(C([C@@H](NC([C@H](CC3=CC(F)=CC=C3)NC(/C=C/CCC)=O)=O)CO4)=O)CCC2)=O)=O)N5C[C@H](C)C[C@@]5([H])C4=O
ClassAcyldepsipeptide analogue
RD_Index1.03 at 25 uM
Site of InteractionNucleotide binding domain
Type of Enzymatic AssaySubstrate degradation assay (FITC-casein)

Structure



HSPMDB002584

ADEP-20

Physicochemical Properties