HSPMdb Accession NoHSPMDB002579
PMID30126533
TargetHsp100
HSP NameClpP
OrganismHuman
LocalizationMitochondria
Enzymatic activityInhibition of protease activity
Compound NameADEP-02
SMILESO=C([C@H](C)NC([C@@]1([H])N(CCCC1)C([C@@]2([H])N(C([C@@H](NC([C@H](CC3=CC=CC=C3)NC(/C=C/CCCC)=O)=O)CO4)=O)CCC2)=O)=O)N5CCC[C@@]5([H])C4=O
ClassAcyldepsipeptide analogue
RD_Index1.08 at 25 uM
Site of InteractionNucleotide binding domain
Type of Enzymatic AssaySubstrate degradation assay (FITC-casein)

Structure



HSPMDB002579

ADEP-02

Physicochemical Properties