HSPMdb Accession NoHSPMDB002575
PMID21855356
TargetHsp100
HSP NameClpP
OrganismBacteria
LocalizationCytosol
Enzymatic activityInhibition of peptidase activity
Compound Name6
IUPAC Name(3R,4R)-3-(N-(tert-Butoxycarbonyl)-9-aminononyl)-4-(dec-9-enyl)oxetan-2-one
SMILESC(C)(C)(C)OC(=O)NCCCCCCCCC[C@H]1C(O[C@@H]1CCCCCCCCC=C)=O
ClassBeta lactone analogue
% Enzymatic Inhibition/Fold Change20% at 600 uM
Site of InteractionNucleotide binding domain
Type of Enzymatic AssayPeptidase assay (SLY-AMC)
Cellular ModelS. aureus
DiseaseBacterial infection

Structure



HSPMDB002575

6

Physicochemical Properties