HSPMdb Accession No | HSPMDB002567 |
PMID | 21855356 |
Target | Hsp100 |
HSP Name | ClpP |
Organism | Bacteria |
Localization | Cytosol |
Enzymatic activity | Inhibition of peptidase activity |
Compound Name | 1 |
IUPAC Name | (3R,4R)-3-(8-Nonenyl)-4-(2-phenylethyl)oxetan-2-one |
SMILES | C(CCCCCCC=C)[C@H]1C(O[C@@H]1CCC1=CC=CC=C1)=O |
Class | Beta lactone analogue |
% Enzymatic Inhibition/Fold Change | 30% at 20 uM |
Site of Interaction | Nucleotide binding domain |
Type of Enzymatic Assay | Peptidase assay (SLY-AMC) |
Cellular Model | S. aureus |
Disease | Bacterial infection |