HSPMdb Accession NoHSPMDB002564
PMID21855356
TargetHsp100
HSP NameClpP
OrganismBacteria
LocalizationCytosol
Enzymatic activityInhibition of peptidase activity
Compound Name1
IUPAC Name(3R,4R)-3-(8-Nonenyl)-4-(2-phenylethyl)oxetan-2-one
SMILESC(CCCCCCC=C)[C@H]1C(O[C@@H]1CCC1=CC=CC=C1)=O
ClassBeta lactone analogue
% Enzymatic Inhibition/Fold Change30% at 10 uM
Site of InteractionNucleotide binding domain
Type of Enzymatic AssayPeptidase assay (SLY-AMC)
Cellular ModelS. aureus
DiseaseBacterial infection

Structure



HSPMDB002564

1

Physicochemical Properties