HSPMdb Accession No | HSPMDB002563 |
PMID | 23361916 |
Target | Hsp100 |
HSP Name | ClpP |
Organism | Bacteria |
Localization | Cytosol |
Enzymatic activity | Inhibition of peptidase activity |
Compound Name | 29 |
IUPAC Name | (3S,4S)-4-(pent-4-yn-1-yl)-3-tridecyloxetan-2-one |
SMILES | CCCCCCCCCCCCC[C@H]1[C@H](CCCC#C)OC1=O |
Class | Beta lactone (library of enantiopure) |
% Enzymatic Inhibition/Fold Change | 20% at 100 uM |
Site of Interaction | Nucleotide binding domain |
Type of Enzymatic Assay | Peptidase assay (SLY-AMC) |
Cellular Model | S. aureus |
Disease | Bacterial infection |