HSPMdb Accession No | HSPMDB002560 |
PMID | 23361916 |
Target | Hsp100 |
HSP Name | ClpP |
Organism | Bacteria |
Localization | Cytosol |
Enzymatic activity | Inhibition of peptidase activity |
Compound Name | 24 |
IUPAC Name | 3-(non-8-en-1-yl)-4-(pent-4-yn-1-yl)oxetan-2-one |
SMILES | [H]C(=C)CCCCCCCC1C(CCCC#C)OC1=O |
Class | Beta lactone (library of enantiopure) |
% Enzymatic Inhibition/Fold Change | 80% at 100 uM |
Site of Interaction | Nucleotide binding domain |
Type of Enzymatic Assay | Peptidase assay (SLY-AMC) |
Cellular Model | E. coli |
Disease | Bacterial infection |