HSPMdb Accession NoHSPMDB002552
PMID23361916
TargetHsp100
HSP NameClpP
OrganismBacteria
LocalizationCytosol
Enzymatic activityInhibition of peptidase activity
Compound Name34
IUPAC Name(3R)-3-(2-phenylethyl)oxetan-2-one
SMILESO=C1OC[C@H]1CCC1=CC=CC=C1
Class Beta lactone (library of enantiopure)
% Enzymatic Inhibition/Fold Change0-5% at 10 uM
Site of InteractionNucleotide binding domain
Type of Enzymatic AssayPeptidase assay (SLY-AMC)
DiseaseBacterial infection

Structure



HSPMDB002552

34

Physicochemical Properties