HSPMdb Accession NoHSPMDB002547
PMID23361916
TargetHsp100
HSP NameClpP
OrganismBacteria
LocalizationCytosol
Enzymatic activityInhibition of peptidase activity
Compound Name32
IUPAC Name3-(2-phenylethyl)oxetan-2-one
SMILESO=C1OCC1CCC1=CC=CC=C2
Class Beta lactone (library of enantiopure)
% Enzymatic Inhibition/Fold Change80% at 100 uM
Site of InteractionNucleotide binding domain
Type of Enzymatic AssayPeptidase assay (SLY-AMC)
DiseaseBacterial infection

Structure



HSPMDB002547

32

Physicochemical Properties