HSPMdb Accession No | HSPMDB002539 |
PMID | 23361916 |
Target | Hsp100 |
HSP Name | ClpP |
Organism | Bacteria |
Localization | Cytosol |
Enzymatic activity | Inhibition of peptidase activity |
Compound Name | 22 |
IUPAC Name | (3R,4R)-3-decyl-4-(5-{[3-(dimethylamino)propyl]sulfanyl}pentyl)oxetan-2-one |
SMILES | CCCCCCCCCC[C@@H]1[C@@H](CCCCCSCCCN(C)C)OC1=O |
Class | Beta lactone (library of enantiopure) |
% Enzymatic Inhibition/Fold Change | 50% at 100 uM |
Site of Interaction | Nucleotide binding domain |
Type of Enzymatic Assay | Peptidase assay (SLY-AMC) |
Disease | Bacterial infection |