HSPMdb Accession NoHSPMDB002538
PMID23361916
TargetHsp100
HSP NameClpP
OrganismBacteria
LocalizationCytosol
Enzymatic activityInhibition of peptidase activity
Compound Name11
IUPAC Name(3S,4S)-3-decyl-4-(5-{[3-(dimethylamino)propyl]sulfanyl}pentyl)oxetan-2-one
SMILESCCCCCCCCCC[C@H]1[C@H](CCCCCSCCCN(C)C)OC1=O
Class Beta lactone (library of enantiopure)
% Enzymatic Inhibition/Fold Change85% at 100 uM
Site of InteractionNucleotide binding domain
Type of Enzymatic AssayPeptidase assay (SLY-AMC)
DiseaseBacterial infection

Structure



HSPMDB002538

11

Physicochemical Properties