HSPMdb Accession NoHSPMDB002535
PMID23361916
TargetHsp100
HSP NameClpP
OrganismBacteria
LocalizationCytosol
Enzymatic activityInhibition of peptidase activity
Compound Name7
IUPAC Name(3-{5-[(2S,3S)-3-decyl-4-oxooxetan-2-yl]pentanesulfonyl}propyl)trimethylazanium iodide
SMILES[I-].CCCCCCCCCC[C@H]1[C@H](CCCCCS(=O)(=O)CCC[N+](C)(C)C)OC1=O
Class Beta lactone (library of enantiopure)
% Enzymatic Inhibition/Fold Change93% at 100 uM
Site of InteractionNucleotide binding domain
Type of Enzymatic AssayPeptidase assay (SLY-AMC)
DiseaseBacterial infection

Structure



HSPMDB002535

7

Physicochemical Properties