HSPMdb Accession No | HSPMDB002534 |
PMID | 23361916 |
Target | Hsp100 |
HSP Name | ClpP |
Organism | Bacteria |
Localization | Cytosol |
Enzymatic activity | Inhibition of peptidase activity |
Compound Name | 5 |
IUPAC Name | (3-{3-[(2S,3S)-3-decyl-4-oxooxetan-2-yl]propanesulfonyl}propyl)trimethylazanium iodide |
SMILES | [I-].CCCCCCCCCC[C@H]1[C@H](CCCS(=O)(=O)CCC[N+](C)(C)C)OC1=O |
Class | Beta lactone (library of enantiopure) |
% Enzymatic Inhibition/Fold Change | 93% at 100 uM |
Site of Interaction | Nucleotide binding domain |
Type of Enzymatic Assay | Peptidase assay (SLY-AMC) |
Disease | Bacterial infection |