HSPMdb Accession NoHSPMDB002531
PMID23361916
TargetHsp100
HSP NameClpP
OrganismBacteria
LocalizationCytosol
Enzymatic activityInhibition of peptidase activity
Compound Name1
IUPAC Name(3S,4S)-3-decyl-4-{2-[3-(dimethylamino)propanesulfonyl]ethyl}oxetan-2-one
SMILESCCCCCCCCCC[C@H]1[C@H](CCS(=O)(=O)CCCN(C)C)OC1=O
Class Beta lactone (library of enantiopure)
% Enzymatic Inhibition/Fold Change80% at 100 uM
Site of InteractionNucleotide binding domain
Type of Enzymatic AssayPeptidase assay (SLY-AMC)
DiseaseBacterial infection

Structure



HSPMDB002531

1

Physicochemical Properties