HSPMdb Accession No | HSPMDB002528 |
PMID | 25937012 |
Target | Hsp100 |
HSP Name | ClpP |
Organism | Bacteria |
Localization | Cytosol |
Enzymatic activity | Inhibition of peptidase activity |
Compound Name | 35 |
IUPAC Name | 4-(dimethylamino)-N-{5-[3-(oct-7-en-1-yl)-4-oxooxetan-2-yl]pentyl}benzamide |
SMILES | CN(C)C1=CC=C(C=C1)C(=O)NCCCCCC1OC(=O)C1CCCCCCC=C |
Class | Beta lactone analogue |
% Enzymatic Inhibition/Fold Change | 70% at 10 uM |
Site of Interaction | Nucleotide binding domain |
Type of Enzymatic Assay | Peptidase assay (SLY-AMC) |