HSPMdb Accession No | HSPMDB002509 |
PMID | 25937012 |
Target | Hsp100 |
HSP Name | ClpP |
Organism | Bacteria |
Localization | Cytosol |
Enzymatic activity | Inhibition of peptidase activity |
Compound Name | 16 |
IUPAC Name | trimethyl(3-{3-[(2R,3R)-4-oxo-3-undecyloxetan-2-yl]propanesulfonyl}propyl)azanium iodide |
SMILES | [I-].CCCCCCCCCCC[C@@H]1[C@@H](CCCS(=O)(=O)CCC[N+](C)(C)C)OC1=O |
Class | Beta lactone analogue |
% Enzymatic Inhibition/Fold Change | 93% at 10 uM |
Site of Interaction | Nucleotide binding domain |
Type of Enzymatic Assay | Peptidase assay (SLY-AMC) |