HSPMdb Accession No | HSPMDB002502 |
PMID | 25937012 |
Target | Hsp100 |
HSP Name | ClpP |
Organism | Bacteria |
Localization | Cytosol |
Enzymatic activity | Inhibition of peptidase activity |
Compound Name | 9 |
IUPAC Name | (3S,4S)-4-(3-{[3-(dimethylamino)propyl]sulfanyl}propyl)-3-undecyloxetan-2-one |
SMILES | CCCCCCCCCCC[C@H]1[C@H](CCCSCCCN(C)C)OC1=O |
Class | Beta lactone analogue |
% Enzymatic Inhibition/Fold Change | 60% at 10 uM |
Site of Interaction | Nucleotide binding domain |
Type of Enzymatic Assay | Peptidase assay (SLY-AMC) |