HSPMdb Accession No | HSPMDB002500 |
PMID | 25937012 |
Target | Hsp100 |
HSP Name | ClpP |
Organism | Bacteria |
Localization | Cytosol |
Enzymatic activity | Inhibition of peptidase activity |
Compound Name | 7 |
IUPAC Name | trimethyl(3-{5-[(2S,3S)-4-oxo-3-undecyloxetan-2-yl]pentanesulfonyl}propyl)azanium iodide |
SMILES | [I-].CCCCCCCCCCC[C@H]1[C@H](CCCCCS(=O)(=O)CCC[N+](C)(C)C)OC1=O |
Class | Beta lactone analogue |
% Enzymatic Inhibition/Fold Change | 99% at 10 uM |
Site of Interaction | Nucleotide binding domain |
Type of Enzymatic Assay | Peptidase assay (SLY-AMC) |