HSPMdb Accession No | HSPMDB002493 |
PMID | 28917450 |
Target | Hsp100 |
HSP Name | ClpP |
Organism | Plasmodium falciparum |
Localization | Cytosol |
Cellular activity | Antiparasitic activity |
Compound Name | 44 |
IUPAC Name | 2-(2-Morpholinoethylthio)-N-(3-phenylpropyl)-pyrimidin-4-one-5-carboxamide |
SMILES | O1CCN(CC1)CCSC1=NC=C(C(N1)=O)C(=O)NCCCC1=CC=CC=C1 |
Class | Library of small molecule structures |
IC50 (µM) | 22 |
Cellular assay | Parasite growth inhibition assay (SYBR green) |
Cellular Model | P. falciparum |
Disease | Malaria |