HSPMdb Accession NoHSPMDB002492
PMID28917450
TargetHsp100
HSP NameClpP
OrganismPlasmodium falciparum
LocalizationCytosol
Cellular activityAntiparasitic activity
Compound Name43
IUPAC Name2-(Morpholinomethyl)-6-oxo-3-phenyl-4,6-dihydropyrimido[2,1-b][1,3]thiazine-7-carboxylic acid
SMILESO1CCN(CC1)CC1=C(CN2C(S1)=NC=C(C2=O)C(=O)O)C2=CC=CC=C2
ClassLibrary of small molecule structures
IC50 (µM)11
Cellular assayParasite growth inhibition assay (SYBR green)
Cellular ModelP. falciparum
DiseaseMalaria

Structure



HSPMDB002492

43

Physicochemical Properties