HSPMdb Accession No | HSPMDB002491 |
PMID | 28917450 |
Target | Hsp100 |
HSP Name | ClpP |
Organism | Plasmodium falciparum |
Localization | Cytosol |
Cellular activity | Antiparasitic activity |
Compound Name | 42 |
IUPAC Name | Ethyl 2-(2-morpholinoethylthio)-1-(2-oxo-2-phenylethyl)-pyrimidin-4-one-5-carboxylate |
SMILES | O1CCN(CC1)CCSC=1N(C=C(C(N1)=O)C(=O)OCC)CC(C1=CC=CC=C1)=O |
Class | Library of small molecule structures |
IC50 (µM) | 19 |
Cellular assay | Parasite growth inhibition assay (SYBR green) |
Cellular Model | P. falciparum |
Disease | Malaria |