HSPMdb Accession NoHSPMDB002490
PMID28917450
TargetHsp100
HSP NameClpP
OrganismPlasmodium falciparum
LocalizationCytosol
Cellular activityAntiparasitic activity
Compound Name40
IUPAC NameEthyl-2-(2-oxo-2-(2-(2-phenylacetyl)hydrazinyl)ethylthio)-pyrimidin-4-one-5-carboxylate
SMILESC(C)OC(=O)C=1C(NC(=NC1)SCC(NNC(CC1=CC=CC=C1)=O)=O)=O
ClassLibrary of small molecule structures
IC50 (µM)82.5
Cellular assayParasite growth inhibition assay (SYBR green)
Cellular ModelP. falciparum
DiseaseMalaria

Structure



HSPMDB002490

40

Physicochemical Properties