HSPMdb Accession No | HSPMDB002490 |
PMID | 28917450 |
Target | Hsp100 |
HSP Name | ClpP |
Organism | Plasmodium falciparum |
Localization | Cytosol |
Cellular activity | Antiparasitic activity |
Compound Name | 40 |
IUPAC Name | Ethyl-2-(2-oxo-2-(2-(2-phenylacetyl)hydrazinyl)ethylthio)-pyrimidin-4-one-5-carboxylate |
SMILES | C(C)OC(=O)C=1C(NC(=NC1)SCC(NNC(CC1=CC=CC=C1)=O)=O)=O |
Class | Library of small molecule structures |
IC50 (µM) | 82.5 |
Cellular assay | Parasite growth inhibition assay (SYBR green) |
Cellular Model | P. falciparum |
Disease | Malaria |