HSPMdb Accession NoHSPMDB002488
PMID28917450
TargetHsp100
HSP NameClpP
OrganismPlasmodium falciparum
LocalizationCytosol
Cellular activityAntiparasitic activity
Compound Name37
IUPAC Name1-Benzyl-2-(2-(4-cyanophenyl)-2-oxoethylthio)-6-oxo-N-(3-phenylpropyl)-1,6-dihydropyrimidine-5-carboxamide
SMILESC(C1=CC=CC=C1)N1C(=NC=C(C1=O)C(=O)NCCCC1=CC=CC=C1)SCC(=O)C1=CC=C(C=C1)C#N
ClassLibrary of small molecule structures
IC50 (µM)13.7
Cellular assayParasite growth inhibition assay (SYBR green)
Cellular ModelP. falciparum
DiseaseMalaria

Structure



HSPMDB002488

37

Physicochemical Properties