HSPMdb Accession No | HSPMDB002488 |
PMID | 28917450 |
Target | Hsp100 |
HSP Name | ClpP |
Organism | Plasmodium falciparum |
Localization | Cytosol |
Cellular activity | Antiparasitic activity |
Compound Name | 37 |
IUPAC Name | 1-Benzyl-2-(2-(4-cyanophenyl)-2-oxoethylthio)-6-oxo-N-(3-phenylpropyl)-1,6-dihydropyrimidine-5-carboxamide |
SMILES | C(C1=CC=CC=C1)N1C(=NC=C(C1=O)C(=O)NCCCC1=CC=CC=C1)SCC(=O)C1=CC=C(C=C1)C#N |
Class | Library of small molecule structures |
IC50 (µM) | 13.7 |
Cellular assay | Parasite growth inhibition assay (SYBR green) |
Cellular Model | P. falciparum |
Disease | Malaria |