HSPMdb Accession NoHSPMDB002486
PMID28917450
TargetHsp100
HSP NameClpP
OrganismPlasmodium falciparum
LocalizationCytosol
Cellular activityAntiparasitic activity
Compound Name35
IUPAC Name1-Benzyl-2-(2-(4-(diethylamino)phenyl)-2-oxoethylthio)-6-oxo-N-(3-phenylpropyl)-1,6-dihydropyrimidine-5-carboxamide
SMILESOc1ccc(cc1)C(=O)CSC2=NC=C(C(=O)NCCCc3ccccc3)C(=O)N2Cc4ccccc4
ClassLibrary of small molecule structures
IC50 (µM)9.2
Cellular assayParasite growth inhibition assay (SYBR green)
Cellular ModelP. falciparum
DiseaseMalaria

Structure



HSPMDB002486

35

Physicochemical Properties