HSPMdb Accession NoHSPMDB002485
PMID28917450
TargetHsp100
HSP NameClpP
OrganismPlasmodium falciparum
LocalizationCytosol
Cellular activityAntiparasitic activity
Compound Name34
IUPAC NameEthyl-2-(1-benzyl-6-oxo-5-(3-phenylpropylcarbamoyl)-1,6-dihydropyrimidin-2-ylthio)acetate
SMILESCCN(CC)c1ccc(cc1)C(=O)CSC2=NC=C(C(=O)NCCCc3ccccc3)C(=O)N2Cc4ccccc4
ClassLibrary of small molecule structures
IC50 (µM)15.9
Cellular assayParasite growth inhibition assay (SYBR green)
Cellular ModelP. falciparum
DiseaseMalaria

Structure



HSPMDB002485

34

Physicochemical Properties