HSPMdb Accession NoHSPMDB002483
PMID28917450
TargetHsp100
HSP NameClpP
OrganismPlasmodium falciparum
LocalizationCytosol
Cellular activityAntiparasitic activity
Compound Name31
IUPAC Name1-Benzyl-2-(2-(4-methoxyphenyl)-2-oxoethylthio)-6-oxo-N-(3-phenylpropyl)-1,6 dihydropyrimidine-5-carboxamide
SMILESO=C(CSC1=NC=C(C(=O)NCCCc2ccccc2)C(=O)N1Cc3ccccc3)NNC(=O)Cc4ccccc4
ClassLibrary of small molecule structures
IC50 (µM)2.4
Cellular assayParasite growth inhibition assay (SYBR green)
Cellular ModelP. falciparum
DiseaseMalaria

Structure



HSPMDB002483

31

Physicochemical Properties