HSPMdb Accession NoHSPMDB002481
PMID28917450
TargetHsp100
HSP NameClpP
OrganismPlasmodium falciparum
LocalizationCytosol
Cellular activityAntiparasitic activity
Compound Name26
IUPAC Name2-(2-(2-(4-Cyanophenyl)-2-oxoethylthio)-6-methylpyrimidin-4-yl-thio)-N-(2-phenylacetyl)acetohydrazide
SMILESO=C(CSC1=NC=C(C(=O)NCCCc2ccccc2)C(=O)N1Cc3ccccc3)c4ccccc4
ClassLibrary of small molecule structures
IC50 (µM)12.4
Cellular assayParasite growth inhibition assay (SYBR green)
Cellular ModelP. falciparum
DiseaseMalaria

Structure



HSPMDB002481

26

Physicochemical Properties