HSPMdb Accession No | HSPMDB002480 |
PMID | 28917450 |
Target | Hsp100 |
HSP Name | ClpP |
Organism | Plasmodium falciparum |
Localization | Cytosol |
Cellular activity | Antiparasitic activity |
Compound Name | 25 |
IUPAC Name | 2-(6-Methyl-2-(2-morpholinoethylthio)pyrimidin-4-yl-thio)-N-(2-phenylacetyl)acetohydrazide |
SMILES | CC1=CC(=NC(=N1)SCCN1CCOCC1)SCC(=O)N(N)C(CC1=CC=CC=C1)=O |
Class | Library of small molecule structures |
IC50 (µM) | 14.4 |
Cellular assay | Parasite growth inhibition assay (SYBR green) |
Cellular Model | P. falciparum |
Disease | Malaria |