HSPMdb Accession No | HSPMDB002478 |
PMID | 28917450 |
Target | Hsp100 |
HSP Name | ClpP |
Organism | Plasmodium falciparum |
Localization | Cytosol |
Cellular activity | Antiparasitic activity |
Compound Name | 23 |
IUPAC Name | 2-(2-(2-(4-(Diethylamino)phenyl)-2-oxoethylthio)-6-methylpyrimidin-4-yl-thio)-N-(2-phenylacetyl)acetohydrazide |
SMILES | C(C)N(C1=CC=C(C=C1)C(CSC1=NC(=CC(=N1)SCC(=O)N(N)C(CC1=CC=CC=C1)=O)C)=O)CC |
Class | Library of small molecule structures |
IC50 (µM) | 12.14 |
Cellular assay | Parasite growth inhibition assay (SYBR green) |
Cellular Model | P. falciparum |
Disease | Malaria |