HSPMdb Accession No | HSPMDB002476 |
PMID | 28917450 |
Target | Hsp100 |
HSP Name | ClpP |
Organism | Plasmodium falciparum |
Localization | Cytosol |
Cellular activity | Antiparasitic activity |
Compound Name | 11 |
IUPAC Name | 2-{[3-oxo-4-(2-phenylethyl)-12-(propan-2-yl)-11-oxa-8-thia-4,6-diazatricyclo[7.4.0.0²,?]trideca-1(9),2(7),5-trien-5-yl]sulfanyl}-N-(4-phenylbutan-2-yl)acetamide |
SMILES | CC(CCC1=CC=CC=C1)NC(=O)CSC1=NC2=C(C3=C(COC(C3)C(C)C)S2)C(=O)N1CCC1=CC=CC=C1 |
Class | Library of small molecule structures |
IC50 (µM) | 25 |
Cellular assay | Parasite growth inhibition assay (SYBR green) |
Cellular Model | P. falciparum |
Disease | Malaria |