HSPMdb Accession No | HSPMDB002475 |
PMID | 28917450 |
Target | Hsp100 |
HSP Name | ClpP |
Organism | Plasmodium falciparum |
Localization | Cytosol |
Cellular activity | Antiparasitic activity |
Compound Name | 6 |
IUPAC Name | 2-((6-Methyl-2-((2-oxo-2-phenylethyl)thio)pyrimidin-4-yl)thio)-N0-(2-phenylacetyl)acetohydrazide |
SMILES | CCCCOc1ccc(c(C)c1)c2nn(cc2\C=C(C#N)\C(=O)NCc3occc3)c4ccccc4 |
Class | Library of small molecule structures |
IC50 (µM) | 75 |
Cellular assay | Parasite growth inhibition assay (SYBR green) |
Cellular Model | P. falciparum |
Disease | Malaria |