HSPMdb Accession NoHSPMDB002475
PMID28917450
TargetHsp100
HSP NameClpP
OrganismPlasmodium falciparum
LocalizationCytosol
Cellular activityAntiparasitic activity
Compound Name6
IUPAC Name2-((6-Methyl-2-((2-oxo-2-phenylethyl)thio)pyrimidin-4-yl)thio)-N0-(2-phenylacetyl)acetohydrazide
SMILESCCCCOc1ccc(c(C)c1)c2nn(cc2\C=C(C#N)\C(=O)NCc3occc3)c4ccccc4
ClassLibrary of small molecule structures
IC50 (µM)75
Cellular assayParasite growth inhibition assay (SYBR green)
Cellular ModelP. falciparum
DiseaseMalaria

Structure



HSPMDB002475

6

Physicochemical Properties