HSPMdb Accession No | HSPMDB002474 |
PMID | 28917450 |
Target | Hsp100 |
HSP Name | ClpP |
Organism | Plasmodium falciparum |
Localization | Cytosol |
Cellular activity | Antiparasitic activity |
Compound Name | 1 |
IUPAC Name | N-(5-Ethyl-1,3,4-thiadiazol-2-yl)-2-((5-(3-hydroxynaphthalen-2-yl)-4-(2-methoxyethyl)-4H-1,2,4-triazol-3-yl)thio)acetamide |
SMILES | C(C)C1=NN=C(S1)NC(CSC1=NN=C(N1CCOC)C1=CC2=CC=CC=C2C=C1O)=O |
Class | Library of small molecule structures |
IC50 (µM) | 27 |
Cellular assay | Parasite growth inhibition assay (SYBR green) |
Cellular Model | P. falciparum |
Disease | Malaria |