HSPMdb Accession NoHSPMDB002474
PMID28917450
TargetHsp100
HSP NameClpP
OrganismPlasmodium falciparum
LocalizationCytosol
Cellular activityAntiparasitic activity
Compound Name1
IUPAC NameN-(5-Ethyl-1,3,4-thiadiazol-2-yl)-2-((5-(3-hydroxynaphthalen-2-yl)-4-(2-methoxyethyl)-4H-1,2,4-triazol-3-yl)thio)acetamide
SMILESC(C)C1=NN=C(S1)NC(CSC1=NN=C(N1CCOC)C1=CC2=CC=CC=C2C=C1O)=O
ClassLibrary of small molecule structures
IC50 (µM)27
Cellular assayParasite growth inhibition assay (SYBR green)
Cellular ModelP. falciparum
DiseaseMalaria

Structure



HSPMDB002474

1

Physicochemical Properties