HSPMdb Accession No | HSPMDB002473 |
PMID | 28917450 |
Target | Hsp100 |
HSP Name | ClpP |
Organism | Plasmodium falciparum |
Localization | Cytosol |
Enzymatic activity | Inhibition of protease activity |
Compound Name | 44 |
IUPAC Name | 2-(2-Morpholinoethylthio)-N-(3-phenylpropyl)-pyrimidin-4-one-5-carboxamide |
SMILES | CCc1sc(NC(=O)CSc2nnc(n2CCOC)c3cc4ccccc4cc3O)nn1 |
Class | Library of small molecule structures |
Ki (µM) | 18 |
Site of Interaction | Nucleotide binding domain |
Type of Enzymatic Assay | Peptidase assay (SLY-AMC) |
Cellular Model | P. falciparum |
Disease | Malaria |